Treatment of OVA-induced AHR mice with ST2 and IL-33 blocking antibodies was also found to ameliorate airway inflammation, which highlights the great promise that IL-33 neutralizing therapies hold in the treatment of asthma (Lohning et al., 1998; Coyle et al., 1999; Liu et al., 2009). The gene discussed is IL33; the disease is asthma.