MTOR and leukemia: New therapeutic approaches are thus warranted [3], and inhibition of the phosphatidylinositol 3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) pathway may become a future strategy because this pathway is constitutively activated in the leukemia cells for most patients and seems important for regulation of cell proliferation, viability, and autophagy [4–8].