C-C type chemokine receptor (CCR)5 and macrophage inflammatory protein (MIP)1β, a Th1-related chemokine receptor and its ligand, were detected in the intestinal lesions in patients with BD, and we suggested that CCR5/MIP1β interaction played a role in the migration of activated Th1 cells [8]. This evidence concerns the gene CCR5 and Behcet disease.