DSCAM and Down syndrome: Similar to our previous study of the DA system, we used the two effectors Dendrite-Specific Drosophila Down Syndrome Cell Adhesion Molecule, conjugated to GFP (Dscam[17.1]::GFP) (postsynaptic; Figure 4A and 4C) and neuronal synaptobrevin, conjugated to GFP (n-syb::GFP) (presynaptic; Figure 4B and 4D) [67], [68].