IL6 and nutritional deficiency disease: Studies of malnourished children have shown that Protein-Energy Malnutrition may lead to oxidative stress, which can lead to increased activity of proinflammatory cytokines [45], this finding is in accordance with our following researches about increase of serum proinflammatory cytokines concentration (IL-6, IL-1) beside oxidative stress markers (data has not been published) such as MDA (Malon-Di-Aldehyde), especially in food deprived and inequality undergoing mice.