IFNG and neoplasm: The kinetic low-dose CD25 Ab depletion group generated the highest numbers of IFN-γ-secreting, mesothelin-specific T lymphocytes (83.7±2.0) compared to the other groups after 14 days of WF-3 tumor challenge (PBS group 16.0±2.3, sequential high dose CD25 Ab group 32.0±4.6, sequential low dose CD25 Ab group 22.0±1.2, p<0.001, one-way ANOVA) (Fig. 6C2).