IL10 and granulomatosis with polyangiitis: In contrast, IL-10+ Tregs did not differ between quiescent GPA (0.7 ± 0.4% in untreated patients, n = 26; 0.5 ± 0.2% in treated patients, n = 16) or active GPA (0.6 ± 0.4%, n = 17) compared to the HC (0.5 ± 0.3%, n = 14) (P = 0.13, P = 0.7, and P = 0.52 respectively, for comparison with the HC) (Figure 2A).