In a separate study where cystic fibrosis IB3 epithelial cells have diminished levels of SHIP1 mRNAs compared to normal IB3 epithelial cells, treatment of fibrosis IB3 epithelial cells with miR-155 inhibitors led to increased luciferase activity associated with normal IB3 SHIP1 levels [135]. Here, INPP5D is linked to cystic fibrosis.