The aim of present study was to evaluate the frequencies of the VEGF −2578C>A, −1154G>A, −634G>C, and 936C>T and KDR −604T>C (rs2071559), 1192G>A (rs2305948), and 1719T>A (rs1870377) polymorphisms in Korean patients with moyamoya disease in an effort to determine the relationship of these polymorphisms with moyamoya disease. This evidence concerns the gene VEGFA and Moyamoya disease.