The staining intensity of E-cadherin on SCC cells was significantly associated with lymph node involvement (p= 0.049), distant metastasis (p= 0.001), and tumor differentiation (p= 0.041), while the intensity of Vimentin staining was associated with lymph node involvement (p= 0.009) and distant metastasis (p= 0.002). The gene discussed is VIM; the disease is neoplasm.