TBX1 and neoplasm: Nuclear staining intensity of Brachyury in SCC cells was significantly associated with clinical T stage (p=0.001), lymph node involvement (p= 0.003), tumor differentiation (p=0.043), and the pattern of invasion (p=0.024), while cytoplasmic intensity of Brachyury was associated only with lymph node involvement (p=0.028) and the pattern of invasion (p=0.022).