CEACAM5 and neoplasm: For the first postoperative follow-up visit, the levels of CA 15-3, CEA and TPS did not change after tumor resection (p = 0.9655 for CA 15-3, p = 0.0727 for CEA, p = 0.3868 for TPS, Wilcoxon signed rank test); whereas after four cycles of chemotherapy, serum levels of CA 15-3 and CEA instead underwent an elevation (p<0.0001 for CA 15-3, p = 0.0727 for CEA, Wilcoxon signed rank test) (Figure 2B–D), compared with the declined trend of serum miR-155.