The recent meta-analysis and replication study by the US Parkinson Disease GWAS Consortium [10] further strengthened the evidence for association of five previously reported risk loci near the genes for alpha-synuclein (SNCA), microtubule associated protein tau (MAPT), cyclin G-associated kinase (GAK), beta-glucocerebrosidase (GBA), and the major histocompatibility complex locus (HLA) and identified a novel risk locus near the gene Ras-like without CAAX 2 (RIT2). The gene discussed is GAK; the disease is Parkinson disease.