Moreover, base mutation of seed sequence in the 3′-UTR of Stmn1 significantly reduced the binding capacity of miR-101 and 3′-UTR of Stmn1. The overexpression of Stmn1 in human breast cancer tissues correlated with general predictive factors and not restricted to a specific sub-group of breast carcinoma [22]–[24]. The gene discussed is STMN1; the disease is breast carcinoma.