In contrast, NFκB activity was not significantly increased in the lungs of SRA−/− mice with polymicrobial sepsis (14.12% and 5.05% vs. SRA−/− control and sham mice, respectively; p>0.05), and was significantly less than that of the lungs from WT CLP mice (45.49%; p<0.05). The gene discussed is NFKB1; the disease is Sepsis.