BMI-1 overexpression was found in the de novo AML (median: 0.303, p <0.001), CML-CP (median: 0.295, p=0.006), and CML-BC (median: 0.109, p=0.01) groups in comparison with the HI group (median: 0.027); the BMI-1 expression level in the AML-CR group (median: 0.078) was not significantly different compared with the HI group (p=0.322). Here, BMI1 is linked to acute myeloid leukemia.