NQO1 and Decreased total leukocyte count: Low NQO1 activity, implied by the presence of NQO1 gene C609T polymorphism, has been shown in therapy-related myeloid neoplasms [13], benzene exposure associated leukopenias [6,14], infant leukemias associated with MLL gene rearrangements [15] and a subset of de novo AML [5].