CADM1 and sarcoma: Since CADM1 isoforms have different functions in MCs and there are marked differences in expression of CADM1 isoforms in human and mouse MCs, the aim of this study was (i) to identify all CADM1 isoforms expressed in differentiated human HLMCs and the neoplastic MC lines HMC-1 and LAD2, which were derived from patients with MC leukaemia/sarcoma (Butterfield et al., 1988; Kirshenbaum et al., 2003) and (ii) investigate the roles of HLMC-specific isoforms in MC adhesion.