HIF1A and chronic kidney disease: This cross-sectional study aimed at assessing the effect of CKD as well as maintenance HD on plasma oxidative stress markers [total anti-oxidant capacity (TAC), total peroxide (TPX) and oxidative stress index (OSI)] and standard hypoxia biomarkers [lactate, pyruvate and lactate/pyruvate (L/P) ratio, and VEGF] as well as HIF-1α in CKD pediatric patients before and after HD session.