ITGAX and ovarian carcinoma: Interestingly, populations of CD11c+ leukocytes isolated from freshly dispersed human ovarian cancer express endothelial as well as DC markers, indicating that tumor cell-derived β-defensin molecules may contribute to the recruitment and, in the presence of VEGF-A, endothelial cell-like differentiation of CD11c+ DCs in human ovarian cancer (Conejo-Garcia et al., 2004).