Moreover, anti-thyroglobulin and anti-microsome peroxidase antibodies are detected in autoimmune thyroiditis even in the absence of functional impairment; Coombs antibodies, anti-platelets antibodies, and anti-neutrophils antibodies are often present in autoimmune cytopenias; anti-smooth muscle (ASMA) and anti-liver-kidney-muscle (anti-LKM) antibodies are positive in autoimmune hepatitis. The gene discussed is TG; the disease is autoimmune hepatitis.