In the univariate analysis there was no association between traditional aPLs (aCL IgA/G/M and β2GPI IgA/G/M), newer β2GPI sub-classes (D 4/5 IgA and D1 IgG), or aPS/PT IgM with either the composite endpoint or the clinical endpoint of stroke or death. The gene discussed is CD40LG; the disease is stroke disorder.