The result is particularly interesting in the context of (a) cancer, as many cancers show increased expression of DUSP1 and reduced expression of DUSP2, and (b) tumor related conditions such as hypoxia, where low oxygen levels upregulate DUSP1 and downregulate DUSP2 (Patterson et al., 2009; Lin et al., 2011). This evidence concerns the gene DUSP2 and cancer.