BDNF, a member of the nerve growth factor (NGF) family, and its receptor TrkB are widely distributed throughout the brain (Wetmore et al., 1990; Altar et al., 1994), and have a role in synaptic plasticity (Chao, 2003) associated with alcohol addiction (Uhl et al., 2001) and several psychiatric disorders (Martinowich et al., 2007). Here, NGF is linked to Addictive alcohol use.