XCL1 and inflammatory bowel disease: We found that lymphotactin, produced by and chemotactic for NK cells, was increased with disease and decreased following anti-IL-7Rα M595 treatment in both Rag2−/− and Mdr1a−/− mice infected with Hb. A regulatory role for NK cells was demonstrated in one adoptive transfer model of IBD [23], whereas another study showed NK cells neither suppressed nor exacerbated adoptive transfer-induced IBD [24].