Of the 35 SNPs examined, statistically significant (p<0.05) associations were seen for VEGFA rs9367173 and rs6905288 with biliary stones, IL8 rs10805066 with gallbladder and ampulla of Vater cancers, and RNASEL rs672527 with ampulla of Vater cancer (Table 2). The gene discussed is CXCL8; the disease is ampulla of vater cancer.