Although we extended the analysis of common genetic variants to approximately 80% coverage for VEGFA (chr6: 43827369–43870265), 90% for RNASEL (chr1: 180805238–180826133) and 75% for IL8 (chr4: 74831698–74808648), none of the overall effects for each of the tested genes resulted in significant associations at the 0.05 level with either biliary stones or cancer. The gene discussed is CXCL8; the disease is cancer.