Other frequent mutations recently described in AML affect the oncogenes N- and K-Ras and other genes like MLL (mixed-lineage leukemia), RUNX1 (runt-related transcription factor 1), KIT (feline sarcoma viral oncogene homolog), and WT1 (Wilms' tumor 1). The gene discussed is KMT2A; the disease is acute myeloid leukemia.