Kumar et al. retrospectively correlated EGFR and p16 protein expression (a marker of oncogenically active HPV infection) in oropharyngeal tumors- and found that patients whose tumors expressed low EGFR and high p16 had better clinical outcomes in comparison to those whose tumors expressed high EGFR and low p16 [15]. This evidence concerns the gene EGFR and neoplasm of oropharynx.