We assigned an ING4 IHC score for each tumor sample by averaging the scores between “double” and “triple punches” on TMAs and defined less than 1.5 (<1.5) scores as “low ING4” and greater than or equal to 1.5 (≥1.5) scores as “high ING4.” We observed that 77 tumors among 227 tumors scored <1.5, constituting 34% of tumor samples that expressed low levels of ING4 (Table 1). This evidence concerns the gene ING4 and neoplasm.