Immunohistochemical labeling of the carcinoma tissue samples in TMA demonstrated IGF-1 and TGF-β1 expression by both carcinoma cells and stromal fibroblasts in many of the tumors (Fig. S5) but failed to detect a correlation between response to inhibitors in co-culture and growth factor labeling in the stromal fibroblasts. The gene discussed is TGFB1; the disease is carcinoma.