Similarly, α-bisabolol concentration in the membrane and nuclei cellular fraction of BCR-ABL+ cells (113±4, 273±36 and 101±64 pmol/106 cells for K562, LAMA-84 and CML-T1, respectively) is 4 to 10-fold higher than in normal PBMC (26±10 pmol/106 cells, figure 4). This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.