POSTN and metastatic malignant neoplasm in the lymph nodes: After universal analysis, periostin was observed to be related to tumor size, histological grade, lymph node metastasis, postoperative distant metastasis, triple-negative breast cancer, and CSC ratio (P = 0.01, 0.003, 0.001, 0.001, 0.001, and 0.001 respectively) (Table 1).