Neither FXR nor NDRG2 seemed significantly down-regulated in the combined set of 13 tested non-HCC liver-disease cDNA samples originating from patients with liver cirrhosis (n = 5), fatty liver (n = 5) and chronic hepatitis (n = 3) compared to “normal” liver (Fig. 3C). This evidence concerns the gene NR1H4 and cirrhosis of liver.