MCL1 and neoplasm: In addition, Mott et al. (2007) have demonstrated that MCL1, encoding an antiapoptotic BCL2 family protein, is one of the targets of miR-29 family, and that miR-29 miRNAs regulate apoptosis by targeting MCL1. These findings suggest that miR-29 family act as tumor suppressors by targeting DNMT3A, DNMT3B, and MCL1.