CASP3 and neoplasm: In this context, the inhibitory effect of dietary GSPs on the growth of tumor xenograft in athymic nude mice was studied and found to be associated with the: (i) control of cell cycle regulation, and (ii) induction of apoptotic cell death of tumor cells, as indicated by the analysis of the proteins of Bcl-2 family, TUNEL-positive and activated caspase-3-positive cells in tumor xenograft samples at the termination of the in vivo animal experiments.