In a clinic study of depression [35], a set of SNPs in the ABCB1 gene were reported to predict the response to antidepressant treatment in depressed patients receiving drugs of P-gp substrates, including rs7787082 and rs10248420, which were also identified in the present study (Table 1) and are in strong LD with rs1002205 (Fig. 2). This evidence concerns the gene PGP and depressive symptom measurement.