In another study, a “TTCA” deletion (rs3783553) in the 3′ UTR of IL1A, a gene that induces antitumor cell immunity, was shown to be associated with hepatocellular carcinoma risk, and subsequent experiments showed that the deletion enhances binding of miR-122 and miR-378 to IL1A, reducing its in vivo expression [15]. This evidence concerns the gene IL1A and hepatocellular carcinoma.