Our results, although confirming in a very large number of samples (over 1800 bladder cancer patients were examined) the original observation that BLCAP expression is lost with tumor progression, also showed that BLCAP is over-expressed in approximately 20% of the cases examined, and that strong nuclear expression is linked with poor disease outcome, suggesting that BLACP may also have prognostic value. Here, BLCAP is linked to urinary bladder cancer.