KRAS and pancreatic neoplasm: The performance of the qpure model was demonstrated using three approaches: 1) the leave-one-out cross-validation analysis showed that the predictive power of the qpure model is high; 2) qpure cellularity estimates for five cell lines were all  99; 3) qpure cellularity predictions were strongly correlated (0.87) with cellularity estimates calculated from the allele frequency of KRAS mutations detected by deep amplicon sequencing data within a cohort of 76 pancreatic tumours.