The importance of dectin-1 in antifungal responses is now highlighted in several experimental fungal infection models [5], [9], [10], and the increased susceptibility of dectin-1-deficient mice to C. albicans infections is supported by the discovery of dectin-1-deficient humans with recurrent mucocutaneous candidiasis [11], [12]. This evidence concerns the gene CLEC7A and fungal infectious disease.