With the data obtained so far, we can conclude that the intravenously transplanted hASCs survive, migrate into the brain and alleviate pathology by reducing the number of amyloid plaques and memory impairment of Tg2576 mice by up-regulating IL-10 and VEGF and elevating endogenous neurogenesis and synaptic and dendritic stability. The gene discussed is IL10; the disease is memory impairment.