ZEB1 and posterior polymorphous corneal dystrophy: Mutations in the zinc finger E-box binding homeobox 1 gene (ZEB1; MIM ID #189909) mapping to chromosome 10p11.2 were identified as disease-causing in PPCD3 (MIM ID #609141) and it has been estimated that pathogenic changes within this gene account for approximately 25% of all PPCD cases, with a range from 9%–45% depending on population studied [14]–[16].