MUTYH and colorectal carcinoma: Biallelic mutations in the MUTYH gene (a member of the base excision repair system) accounts for<1% of all CRC, and usually causes an attenuated form of polyposis, although 30% of these patients can manifest as a non-polyposis CRC [12].Identifying individuals with germline mutations that predispose to CRC has significant implications for the clinical management of affected individuals and for their relatives.