Interestingly, whereas the revised version of this manuscript was being prepared, evidences for the role of dual NOX4/NOX1 pharmacological inhibitors in decreasing both the apparition of fibrogenic markers and hepatocyte apoptosis in vivo, upon bile duct ligation, were reported [32], highlighting the relevant role of NOX1 and NOX4 in liver fibrosis and opening new perspectives for its treatment. Here, NOX1 is linked to Hepatic fibrosis.