CRP and obesity due to melanocortin 4 receptor deficiency: Eiriksdottir et al. [30] reported a significant interaction between BMI and waist circumference with the AA genotype of SNP rs1205 on CRP levels, indicating that this effect could explain why obesity promotes a more stable mRNA through the G allele, and the strong linkage disequilibrium has been found in different blocks of the CRP gene, as well as in the 3′UTR region in the block formed by the SNPs rs1130864 and rs1205.