Immunohistochemical staining revealed that the tumor was diffusely and strongly positive for c-Kit (CD117) (Figure 3), myeloid stem cell antigen (CD34), DOG1, and Ki-67, slightly positive for vimentin, and negative for smooth muscle actin (SMA), neuron-specific enolase (NSE), S-100, and desmin. The gene discussed is ENO2; the disease is neoplasm.