SFRP4 and cancer: sFRP2 was not detected in any of the cell lines (data not shown), and only sFRP4 was differentially expressed between the chemosensitive (A2780) and chemoresistant cancer cell lines (A2780-ADR and A2780-Cis); with A2780 expressing significantly higher mRNA levels of sFRP4 in comparison to the A2780-ADR and A2780-Cis (Figure 1A).