PCSK9 and atherosclerosis: The frequency of the PCSK9 670G allele in patients selected from Universitätsklinikum Hamburg-Eppendorf Martinistrasse, Hamburg, Germany was 5%[47] which lies between that observed in the TexGen population, 4.4% and that reported for the Lipoprotein Coronary Atherosclerosis Study, 7.4% by Chen et al.[48] in their original study.