Risk of death of breast cancer was significantly increased in patients with low levels of Nuc-Stat5a (CSS log-rank P = 0.025; n = 71; Figure 3C; univariate Cox regression HR = 2.75 (1.33, 5.69); P = 0.006; n = 55; Table 3). The gene discussed is NUCB1; the disease is breast carcinoma.