Except ABCA1 that has been found to be mutated in CRC tumour samples [38,39], none of the 15 genes of the present study has previously been associated with the risk of CRC (http://www.ncbi.nlm.nih.gov/; http://www.hugenavigator.net/ CancerGEMKB/home.do) [40]. This evidence concerns the gene ABCA1 and neoplasm.