To investigate the impact of HDAC inhibitors on gene expression induced by wounding, we selected four effectors that were previously found to play essential roles in wound healing and immunity in G. mellonella, namely a matrix metalloproteinase (MMP) that exerts pleiotropic functions during metamorphosis and the immune response [12], IMPI, which specifically inhibits microbial metalloproteinases causing sepsis [16,17], p38 MAP kinase, which contributes to immunity-related signaling, and the defensin-like antibacterial peptide galiomycin [15]. Here, MAPK14 is linked to Sepsis.